Identify diseases caused by oversecretion of adrenal catecholamines. Identify the chemical nature of catecholamines and their biosynthesis and metabolic fate.ĭescribe the biologic consequences of sympatho-adrenal medulla activation and identify the target organs or tissues for catecholamine effects along with the receptor types that mediate their actions.ĭescribe and integrate the interactions of adrenal medullary and cortical hormones in response to stress. Identify the causes and consequences of oversecretion and undersecretion of glucocorticoids, mineralocorticoids, and adrenal androgens. Identify the major mineralocorticoids, their biologic actions, and their target organs or tissues.ĭescribe the regulation of mineralocorticoid secretion and relate this to the regulation of sodium and potassium excretion. Understand the cellular mechanism of action of adrenal cortical hormones and identify their major physiologic actions, particularly during injury and stress. The adrenal glands are located laterally to each side of the spine, encased by the 10th, 11th, and 12th ribs on the left, and the 11th and 12th ribs on the right. Identify the functional anatomy and zones of the adrenal glands and the principal hormones secreted from each zone.ĭescribe and contrast the regulation of synthesis and release of the adrenal steroid hormones (glucocorticoids, mineralocorticoids, and androgens) and the consequences of abnormalities in their biosynthetic pathways.
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